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Editorial

1. Recombinant Proteins: Hopes for Tissue Engineering
Mohammad Morad Farajollahi, Sepideh Hamzehlou, Ahmad Mehdipour, Ali Samadikuchaksaraei*
Bioimpacts. 2012;2(3): 123-125. doi: 10.5681/bi.2012.010
PMCID: PMC3648934     PMID: 23678450     Scopus ID: 84876695772    
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Editorial

2. Targeted Gene Therapy of Cancer: Second Amendment toward Holistic Therapy
Jaleh Barar ORCID, Yadollah Omidi* ORCID
Bioimpacts. 2013;3(2): 49-51. doi: 10.5681/bi.2013.014
PMCID: PMC3713870     PMID: 23878787     Scopus ID: 84881521871    
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Editorial

3. Intrinsic Bio-Signature of Gene Delivery Nanocarriers May Impair Gene Therapy Goals
Jaleh Barar ORCID, Yadollah Omidi* ORCID
Bioimpacts. 2013;3(3): 105-109. doi: 10.5681/bi.2013.028
PMCID: PMC3786791     PMID: 24163801     Scopus ID: 84887341756    
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Editorial

4. Gene therapy for CNS diseases – Krabbe disease
Mohammad A. Rafi*
Bioimpacts. 2016;6(2): 69-70. doi: 10.15171/bi.2016.09
PMCID: PMC4981250     PMID: 27525222     Scopus ID: 84983541817    
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Review

5. Gene and Stem Cell Therapy: Alone or in Combination?
Mohammad A. Rafi*
Bioimpacts. 2011;1(4): 213-218. doi: 10.5681/bi.2011.030
PMCID: PMC3648974     PMID: 23678430     Scopus ID: 84876718825    
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Review

6. Translational Approaches towards Cancer Gene Therapy: Hurdles and Hopes
Jaleh Barar ORCID, Yadollah Omidi* ORCID
Bioimpacts. 2012;2(3): 127-143. doi: 10.5681/bi.2012.025
PMCID: PMC3648930     PMID: 23678451     Scopus ID: 84874512835    
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Original Research

7. Conditions for combining gene therapy with bone marrow transplantation in murine Krabbe disease
Mohammad A. Rafi ORCID, Paola Luzi, David A. Wenger* ORCID
Bioimpacts. 2020;10(2): 105-115. doi: 10.34172/bi.2020.13
PMCID: PMC7186542     PMID: 32363154     Scopus ID: 85090729388    
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Krabbe disease (KD) is an autosomal recessive lysosomal disorder that imposes defective myelination in the peripheral and central nervous systems. Twitcher combining bone marrow transplantation with AAVrh10-mGALC can have a great extension of life in the murine model of KD.
Original Research

8. Can early treatment of twitcher mice with high dose AAVrh10-GALC eliminate the need for BMT?

Mohammad A Rafi* ORCID, Paola Luzi, David A Wenger ORCID
BioImpacts. 2021;11(2): 135-146. doi: 10.34172/bi.2021.21
PMCID: PMC8022232     PMID: 33842284     Scopus ID: 85106877684    
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Our results demonstrate that, it may be possible to treat human KD patients with high dose AAVrh10 without blood stem cell transplantation which would eliminate the side effects of HSCT.
Mini Review

9. Krabbe disease: A personal perspective and hypothesis
Mohammad A. Rafi* ORCID
Bioimpacts. 2022;12(1): 3-7. doi: 10.34172/bi.2021.23931
PMCID: PMC8783082     PMID: 35087711     Scopus ID: 85127157009    
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Cutting viral dose in half or using BM cells from heterozygote mice in a combination of BMT and gene therapy treatments result in a similar reduction in lifespan of the treated mice.

As a peer-reviewed international open-access journal, BioImpacts publishes articles on basic and translational aspects of pharmaceutical and biomedical sciences. 
Acceptance rate: 24% 
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